A high aspect ratio microelectrode array for mapping neural activity in vitro
نویسندگان
چکیده
منابع مشابه
Spatiotemporal norepinephrine mapping using a high-density CMOS microelectrode array.
A high-density amperometric electrode array containing 8192 individually addressable platinum working electrodes with an integrated potentiostat fabricated using Complementary Metal Oxide Semiconductor (CMOS) processes is reported. The array was designed to enable electrochemical imaging of chemical gradients with high spatiotemporal resolution. Electrodes are arranged over a 2 mm × 2 mm surfac...
متن کاملIn vitro microelectrode array technology and neural recordings.
In vitro microelectrode array (MEA) technology has evolved into a widely used and effective methodology to study cultured neural networks. An MEA forms a unique electrical interface with the cultured neurons in that neurons are directly grown on top of the electrode (neuron-on-electrode configuration). Theoretical models and experimental results suggest that physical configuration and biologica...
متن کاملHigh aspect ratio silicon wire array photoelectrochemical cells.
A key constraint in photon absorbers for solar energy conversion is that the material must be sufficiently thick to absorb most of the solar photons with energies above the material’s band gap, yet sufficiently pure to have a high minority carrier diffusion length for effective collection of the photogenerated charge carriers. This constraint imposes a cost floor on the absorber material by dic...
متن کاملRecent Trends in Microelectrode Array Technology for In Vitro Neural Interface Platform
Microelectrode array (MEA) technology is a widely used platform for the study of in vitro neural networks as it can either record or stimulate neurons by accessing multiple sites of neural circuits simultaneously. Unlike intracellular recording techniques, MEAs form noninvasive interface with cells so that they provides relatively long time window for studying neural circuits. As the technology...
متن کاملHigh-throughput, Continuous-flow Separation of Biomolecules in a High- aspect-ratio Nanofilter Array
We have developed a novel fabrication ap proach to generate massively-parallel, highaspect-ratio vertical nanofluidic channels with smooth, vertical sidewalls and precise control of uniform gap sizes (lateral trench width) down to 50 nm (Figure 1) [1]. The aspect ratio can be as high as 400 and the channel depths are more than 20 μm. This technique enables us to fabricate a large area of solid ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroscience Methods
سال: 2012
ISSN: 0165-0270
DOI: 10.1016/j.jneumeth.2011.11.027